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The main differences are inert ingredients, how the pill looks (color, size), and of course price. Before a generic drug is permitted by the FDA, manufacturers must prove that it works the same way and just as well as the brand name drug. The shape and the color must not be similar to the ones of the brand-name drugs. The price difference is usually quite a bit. Important Information Your doctor must be made aware of your medical history and current medications that you take. Your physician may not prescribe Cardizem (either generic or brand name) if you have ever had a reaction to a similar medication. Also, if you suffer from kidney, liver disease, congestive heart failure, or sick sinus syndrome your doctor will prescribe an alternative medication to help control your hypertension. comparison viagra cialus levitra holistic viagra discount prescription cialis using cialis with viagra